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Friday, June 9, 2017

timesofsandiego : reported that Scripps Vaccine Blocks Heroin 'High,' May Be Key to Opioid Crisis

— City News ServiceScripps Vaccine Blocks Substance abuse 'High,' May Be Key to Opioid Crisis was last modified: by>> Subscribe to Times of San Diego's free daily email newsletter! The vaccine works by exposing the immune system to a part of the heroin molecule's structure, which teaches the immune system to produce antibodies against heroin and its psychoactive products. Share This Article:The Scripps Research Institute of La Jolla announced Tuesday that a vaccine it developed effectively blocks the "high" of heroin in nonhuman primates, based on testing by scientists in Virginia. The scientists said that paid showed a higher level of response this time around, showing a sort of immune system memory. Researchers believe that blocking the high of heroin will help eliminate the motivation for many recovering addicts to relapse into drug use.


New Vaccine Could Stop Heroin Abuse by Blocking High, Study Suggests


New Vaccine Could Stop Heroin Abuse by Blocking High, Study Suggests
The compound, created by chemists at the Scripps Research Institute, works in a way that's similar to other vaccines. By introducing the immune system to a potential future enemy, antibodies against that invader are ready to attack when the time comes. In this case, the vaccine introduces a piece of the heroin molecule to the immune system. The animals were given three doses of the vaccine, which elicited a successful immune response that neutralized heroin given at varying doses. A vaccine that blocks the high from heroin has just moved one step closer to reality.

Clinically-Viable Heroin Vaccine Developed

Development of a Clinically-Viable Substance abuse Vaccine. Bremer said the new heroin vaccine is different because the researchers took a closer look at the chemistry of the vaccine, studying how well antibodies elicited by the vaccine could bind to drug molecules. The Janda Laboratory at TSRI has been working on their heroin vaccine for over eight years; the researchers had previously tested vaccine candidates under laboratory conditions and in rodents, where the strategy proved effective for neutralizing heroin. The vaccine works by exposing the immune system to a part of the heroin molecule's telltale structure. News Jun 09, 2017 | Original Story from The Scripps Research InstituteA vaccine developed at The Scripps Research Institute (TSRI) to block the "high" of heroin has proven effective in non-human primates.


collected by :Lucy William

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