Scientists begin mid-stage trial of Zika vaccine for first time stat : STAT

Although there are several DNA vaccines licensed for agricultural use, there are currently no licensed DNA vaccines for use in humans. Scientists have begun a Phase 2 trial of a vaccine to protect against the Zika virus, the first time an experimental Zika vaccine has gone beyond initial safety testing. The clinical trial involves a DNA-based vaccine, in which proteins from the Zika virus are placed into small pieces of DNA. "I'm totally intent on getting this vaccine to the point where it can be a usable vaccine," Fauci said during a teleconference for journalists, calling the development of a Zika vaccine "a very high priority" for the NIAID. Several other types of Zika vaccines are also in development, including others at the NIAID.




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The Zika Vaccine platform is based on a strategy VRC scientists used previously to develop a West Nile virus vaccine candidate. "A safe and effective Zika vaccine is urgently needed to prevent the often-devastating birth defects that can result from Zika virus infection during pregnancy. Scientists at NIAID's Vaccine Research Center (VRC) developed the NIAID Zika virus investigational DNA vaccine. Explore further: NIH begins testing investigational Zika vaccine in humans Most people with Zika infection have either no or only mild symptoms, such as fever, rash, joint pain and conjunctivitis (red eyes).


collected by :Lucy William

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