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Thursday, October 20, 2016

Sun Pharma and ICGEB to develop novel dengue vaccine : livemint





as informed in livemint

Sun Pharma and ICGEB to develop novel dengue vaccine

Sun Pharma and ICGEB to develop novel dengue vaccine
Sun Pharma and ICGEB to develop novel dengue vaccine
Sun Pharma and ICGEB had, in May, announced another partnership for development of a botanical drug treating dengue.Photo: Hemant Mishra/MintNew Delhi: Sun Pharmaceutical Industries Ltd and International Centre for Genetic Engineering and Biotechnology (ICGEB) on Wednesday signed an agreement to develop a novel dengue vaccine targeted against all four serotypes of dengue virus (DENV).Developed by ICGEB, the tetravalent dengue vaccine is based on a specifically designed recombinant virus-like particle (VLP) which contains host-receptor binding domains of all the four DENV serotypes.


additionally indiatimes

Sun Pharma, ICGEB tie up to develop dengue vaccine

Sun Pharma, ICGEB tie up to develop dengue vaccine
Sun Pharma, ICGEB tie up to develop dengue vaccine
NEW DELHI: Indian pharmaceutical giant Sun Pharma has partnered with International Centre for Genetic Engineering and Biotechnology (ICGEB) to develop a dengue vaccine that would be safe, effective and affordable.This is their second collaboration focussed on the mosquito-borne virus, the first being their pact to develop a botanical drug 'Cipa'.In the latest agreement, Sun Pharma will fund and support further development of the vaccine candidate—DSV4—that targets all four serotypes (variations) of the dengue virus as well as existing ICGEB know-how and patents.DSV4 is expected to take much less time to develop than vaccines like Sanofi's Dengvaxia, according to Navin Khanna, who led the development of the vaccine candidate at ICGEB over the last decade.Pre-clinical studies on the vaccine have been conducted so far and the toxicology studies on animals are expected to begin next before it is taken to the clinical trial phase, he said.Sun Pharma will get exclusive rights and licences to develop and commercialise this vaccine globally, while ICGEB will receive pre-defined royalty and milestone payments, said the drug maker.


as well gmanetwork

Drug firm assures public of dengue vaccine safety amid call for Senate inquiry

Drug firm assures public of dengue vaccine safety amid call for Senate inquiry
Drug firm assures public of dengue vaccine safety amid call for Senate inquiry



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